aptt reagent filtrates (with contact activators and phospholipids removed) Search Results


aptt reagent filtrates (with contact activators and phospholipids removed)  (Merck KGaA)
90
Merck KGaA aptt reagent filtrates (with contact activators and phospholipids removed)
Effects of <t>activated</t> <t>partial</t> <t>thromboplastin</t> time ( <t>APTT</t> ) reagents, APTT reagent filtrates and contact activators on the activation of nonacog beta pegol (N9‐ GP ) and factor IX ( FIX ) (N9) during the clotting phase of a OS FIX clotting assay. The bars represent relative generation of activated factor IX ( FIX a) activity in the presence of mere buffer (black), APTT reagent (red), APTT reagent filtrate (green), or isolated contact activator (purple). Striped and solid bars show the results obtained with N9 and N9‐ GP , respectively. For each APTT reagent, the generation of FIX a activity was compared to that obtained using N9 in the presence of mere buffer (arbitrarily assigned the value 100%). The APTT reagents are indicated below the graph
Aptt Reagent Filtrates (With Contact Activators And Phospholipids Removed), supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aptt reagent filtrates (with contact activators and phospholipids removed) - by Bioz Stars, 2026-09
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Effects of activated partial thromboplastin time ( APTT ) reagents, APTT reagent filtrates and contact activators on the activation of nonacog beta pegol (N9‐ GP ) and factor IX ( FIX ) (N9) during the clotting phase of a OS FIX clotting assay. The bars represent relative generation of activated factor IX ( FIX a) activity in the presence of mere buffer (black), APTT reagent (red), APTT reagent filtrate (green), or isolated contact activator (purple). Striped and solid bars show the results obtained with N9 and N9‐ GP , respectively. For each APTT reagent, the generation of FIX a activity was compared to that obtained using N9 in the presence of mere buffer (arbitrarily assigned the value 100%). The APTT reagents are indicated below the graph

Journal: Research and Practice in Thrombosis and Haemostasis

Article Title: Underestimation of N‐glyco PEG ylated factor IX one‐stage clotting activity owing to contact activator‐impaired activation

doi: 10.1002/rth2.12046

Figure Lengend Snippet: Effects of activated partial thromboplastin time ( APTT ) reagents, APTT reagent filtrates and contact activators on the activation of nonacog beta pegol (N9‐ GP ) and factor IX ( FIX ) (N9) during the clotting phase of a OS FIX clotting assay. The bars represent relative generation of activated factor IX ( FIX a) activity in the presence of mere buffer (black), APTT reagent (red), APTT reagent filtrate (green), or isolated contact activator (purple). Striped and solid bars show the results obtained with N9 and N9‐ GP , respectively. For each APTT reagent, the generation of FIX a activity was compared to that obtained using N9 in the presence of mere buffer (arbitrarily assigned the value 100%). The APTT reagents are indicated below the graph

Article Snippet: APTT reagent filtrates (with contact activators and phospholipids removed) were prepared by passage through centrifugal filters (Amicon Ultra, Ultracel) from Merck Millipore (Carrigtwohill, Ireland) with a molecular mass cut‐off of 10 or 100 kDa at 14 000 × g for 15 minutes.

Techniques: Activation Assay, Coagulation, Activity Assay, Isolation

Effects of activated partial thromboplastin time ( APTT ) reagents, APTT reagent filtrates and contact activators on activated factor XI ( FXI a) amidolytic activity. Each bar triplet represents relative FXI a activity in the presence of APTT reagent (gray), APTT reagent filtrate (white) or isolated contact activator (black), with the FXI a activity when instead using assay buffer arbitrarily set to 100% (outer left bar). The APTT reagents are indicated below the graph

Journal: Research and Practice in Thrombosis and Haemostasis

Article Title: Underestimation of N‐glyco PEG ylated factor IX one‐stage clotting activity owing to contact activator‐impaired activation

doi: 10.1002/rth2.12046

Figure Lengend Snippet: Effects of activated partial thromboplastin time ( APTT ) reagents, APTT reagent filtrates and contact activators on activated factor XI ( FXI a) amidolytic activity. Each bar triplet represents relative FXI a activity in the presence of APTT reagent (gray), APTT reagent filtrate (white) or isolated contact activator (black), with the FXI a activity when instead using assay buffer arbitrarily set to 100% (outer left bar). The APTT reagents are indicated below the graph

Article Snippet: APTT reagent filtrates (with contact activators and phospholipids removed) were prepared by passage through centrifugal filters (Amicon Ultra, Ultracel) from Merck Millipore (Carrigtwohill, Ireland) with a molecular mass cut‐off of 10 or 100 kDa at 14 000 × g for 15 minutes.

Techniques: Activity Assay, Isolation